A non-invasive colon cancer screening has finally arrived. News Item about the Cologuard test.

What's missing in all the tests, all the double blind studies, is taking into account dynamic decision making under uncertainty. The flexions love the double blinds because it costs 500 million to do one, so you can't do a long range or preventive study, or any study outside of stage 3.

More particularly, what no one takes into account on these blood tests, is that a good one like CEA would be taken by everyone if available as an early aid to decision making.

Let's say it has a 90% true positive rate. And the incidence of the disease is 2%. That makes it about 18% you have the disease if you get the positive. All of those 18% would then take the scope. Let's say that would lead to a 25% increased survival rate. And that 100,000 people took the test. That would save 4,500 lives a year. The point is that with a 5 buck test, everyone would have the incentive to take the test compared to say 5% that take it now.


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