One of the central tenets of this list being counting, I note with curiosity the many posts regarding various anti-aging regimes. A brief scan of the literature suggests that the only such regime to have substantial statistical support is calorie restriction, or dietary restriction as it is referred to in many papers. Am I missing something?

In a similar vein, I note the discussions of various dietary regimes to lose weight. Here too it seems that beyond the obvious less calories/more exercise regime there is little counting to support the effectiveness of the wide variety of diet regimes we hear of. Am I missing something here too?

Finally, there does seems to be good support for what you eat being important. With the weight of the evidence pointing to eating a wide ranging diet being a good idea.

Wrapping those three ideas up, the idea of eating a widely varied diet (foraging in its best sense), and not too much of it, as a general prescription for good health and long life suggests itself.

Objections? Comments?

Dr. Shantanu Nagarkatti writes: 

Last summer a client commissioned me to take a study tour of all the major research centers and practitioners clinics on Anti-aging in the US.

Currently Metformin and Rapamycin are the most popular options. Quercetin and Dasatinib in a senolytic cocktail (single dose) will definitively reverse the age (and consequently the function) of every organ in your body by 15 years. Expect to repeat this course in 3-5 years.

It works and is now in human trials on Progeria patients.

None of the above are US FDA approved but could be taken as an off label use at your own legal risk.


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