Mar

5

 An interesting search for new antibiotics from Komodo dragon blood is taking place. The lizards thrive in local Florida zoos.

1) 'We set out to investigate the blood of the Komodo dragon, to try and find out more about its antimicrobial peptides, referring to small proteins that are part of its immune system," Barney Bishop, a professor at Virginia's George Mason University and lead author of the paper, told Digital Trends. "Komodo dragons have a reputation for having robust immune systems that allow them to live in very difficult environments, and be unaffected by bacteria that can cause all types of disease. They also recover very effectively from injuries and wounds inflicted by other dragons.'

2) "Komodo dragons are the largest living lizards and are the apex predators in their environs. They endure numerous strains of pathogenic bacteria in their saliva and recover from wounds inflicted by other dragons, reflecting the inherent robustness of their innate immune defense. We have employed a custom bioprospecting approach combining partial de novo peptide sequencing with transcriptome assembly to identify cationic antimicrobial peptides from Komodo dragon plasma."


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